Comprehensive Fragment Screening of the SARS-CoV-2 Proteome Explores Novel Chemical Space for Drug DevelopmentArticle Published on 2022-11-142022-11-15 Journal: Angewandte Chemie (International ed. in English) [Category] COVID19(2023년), SARS, 변종, 신약개발, 치료기술, 치료제, [키워드] binding binding site Chemical chemotypes Comprehensive Consensus COVID19-NMR development drug drug design Drug discovery fragment fragment screening functional identify International Intervention Ligand NMR NMR spectroscopy novel performed predict protease Protein Proteins proteome protocol provide public health RNA genome SARS-CoV-2 SARS-CoV-2. Screening Space the SARS-CoV-2 Vaccines variant variants of concern was used [DOI] 10.1002/anie.202205858 PMC 바로가기
Trends in the Use of Face Coverings in Publicly Accessible Spaces During the COVID-19 Pandemic, King County, Washington, November 2020-May 2021COVID-19 팬데믹 기간 동안 공개적으로 접근 가능한 공간에서 안면 가리개 사용 추세, 워싱턴 주 킹 카운티, 2020년 11월-2021년 5월Observational Study Published on 2022-09-012022-09-11 Journal: Public health reports (Washington, D.C. : 1974) [Category] COVID19(2023년), SARS, 변종, 임상, [키워드] 95% CI 95% CIs absence age airport Appropriate calculated Compliance conducted Covering COVID-19 cross-sectional declined estimate evaluate Evaluation face face covering Face mask face mask mandate. group help International airport interval King lowest men mitigate not limited observation observational study prevalence ratio prevalence ratios recorded repeated SARS-CoV-2 SARS-CoV-2 transmission Sex Space transmission of SARS-CoV-2 trend unique vaccination vaccine eligibility viral variant Viral variants Washington widespread [DOI] 10.1177/00333549221100795 PMC 바로가기 [Article Type] Observational Study
Tempo-Spatial Modelling of the Spread of COVID-19 in Urban Spaces도시 공간에서 COVID-19의 확산에 대한 시공간 모델링Article Published on 2022-08-082022-09-11 Journal: International Journal of Environmental Research an [Category] 변종, [키워드] Analysis approach changed city consequence contagious contagious disease COVID-19 COVID-19 pandemic disease disparity distribution evaluate Evolution exceptional explain greater increasingly Infection intensity Malaga pandemic Perspective selected shown social areas social structure socio-spatial structure Space Spain Spread statistical statistical analysis theory urban urban spaces. variable variant [DOI] 10.3390/ijerph19159764 PMC 바로가기 [Article Type] Article
A Biosensor Platform for Point-of-Care SARS-CoV-2 Screening현장 진료 SARS-CoV-2 스크리닝을 위한 바이오센서 플랫폼Article Published on 2022-07-032022-09-11 Journal: Biosensors [Category] COVID19(2023년), SARS, 치료기술, [키워드] agency biosensor calibrated can be used capacitance collected data condition correlation COVID-19 COVID-19 pandemic Economy effective Efficiency facilitated Health hospitalized patients individual inductance Interdigitated electrodes Internet Internet of Things Laboratory LCR less Liquid-crystal display measure offer pandemic Patient platform Portable professional public health readout Research SARS-CoV-2 SARS-CoV-2 particle SARS-CoV-2 particles SARS-CoV-2 patients SARS-CoV-2 testing scientist Screening Smartphone Space Spike protein Spread swab sample swab samples test result virus virus detection virus monitoring. [DOI] 10.3390/bios12070487 PMC 바로가기 [Article Type] Article
Quantifying the COVID19 infection risk due to droplet/aerosol inhalation비말/에어로졸 흡입으로 인한 COVID19 감염 위험 정량화Article Published on 2022-07-012022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, [키워드] ambient Analysis carried COVID-19 COVID19 demonstrated develop disease dose-response model framework Infection infection risk Probability risk risk of infection SARS-CoV2 Space speech strain Transmissibility Transport vaccination variant Version [DOI] 10.1038/s41598-022-14862-y PMC 바로가기 [Article Type] Article
An index of access to essential infrastructure to identify where physical distancing is impossible물리적 거리두기가 불가능한 곳을 식별하기 위한 필수 인프라에 대한 액세스 지수Article Published on 2022-06-142022-09-11 Journal: Nature Communications [Category] 치료법, 치료제, [키워드] addition communicable disease communicable diseases correlated country COVID-19 cases develop disease transmission Effectiveness health systems heterogeneity High-resolution highest highlight Households identify Infectious disease lack missing PDI physical distancing population density Prevent Region Regulation resource risk Space Spread Transmission water [DOI] 10.1038/s41467-022-30812-8 PMC 바로가기 [Article Type] Article
Inter-agency perspective: Translating advances in biomarker discovery and medical countermeasures development between terrestrial and space radiation environmentsResearch article Published on 2022-06-012022-10-05 Journal: Life Sciences in Space Research [Category] 비임상, [키워드] accelerate addition adverse effect approach Biomarker Biomarkers Cancer Cancer patients cellular pathway chronic Critical develop Effect help human population Infectious disease Initially involved kill medical countermeasure Medical countermeasures NASA National Cancer Institute NIAID nuclear organization over overlapping physician Population PROTECT provided Radiation Radiation dose radiation exposure radiological reduce Research Space subject supported sustained terrestrial tissue tissues translation Treatment Tumor tumor cell tumors [DOI] 10.1016/j.lssr.2022.06.004 [Article Type] Research article
Rapid identification of SARS-CoV-2 in the point-of-care using digital PCR-based Dr. PCR™ Di20K COVID-19 Detection Kit without viral RNA extraction바이러스 RNA 추출 없이 디지털 PCR 기반 Dr. PCR™ Di20K COVID-19 Detection Kit를 사용하여 현장 진료에서 SARS-CoV-2의 신속한 식별Article Published on 2022-05-012022-09-11 Journal: Genes & genomics [Category] COVID19(2023년), SARS, 치료기술, [키워드] 2019-nCoV addition assessment biosafety Concordance Contamination COVID-19 cross-over detection Diagnosis diagnostic diagnostic sensitivity diagnostic test diagnostic tests dPCR evaluate evaluated Kappa coefficient limitation pandemic performed POCT point-of-care point-of-care testing pre-diagnosis previous study qRT-PCR qRT-PCR. Rapid reliability reported RNA extraction SARS-CoV-2 sensitivity Sensitivity and specificity Space specificity specimen Spread the WHO viral RNA extraction was measured were measured [DOI] 10.1007/s13258-022-01242-z PMC 바로가기 [Article Type] Article
Approaches to Health Efficiency across the European Space through the Lens of the Health Budget EffortArticle Published on 2022-03-052022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] affecting Analysis budget changes in COVID-19 pandemic Effectiveness efficiency of budget allocation effort European Expenditure Health health system identify Intervention Len measure medium member mitigate outcome pandemic Research resource sanitary vulnerability Social protection Space state statistical [DOI] 10.3390/ijerph19053063 PMC 바로가기 [Article Type] Article
Deep recurrent reinforced learning model to compare the efficacy of targeted local versus national measures on the spread of COVID-19 in the UK영국에서 Covid-19의 확산에 대한 표적화 된 지역과 국가적 조치의 효능을 비교하기위한 깊은 재발 강화 학습 모델Epidemiology Published on 2022-02-212022-09-10 Journal: BMJ Open [Category] COVID19(2023년), Fulltext, MERS, SARS, 변종, [키워드] addition applied Combination correlation coefficient COVID-19 COVID-19 case COVID-19 cases curated deep effective Effectiveness Efficacy England Epidemiology evaluate health informatics high risk highlight hotspot imperative infection control International Local lockdown MAE magnitude mean absolute error measure Measures Model mortalities Mortality National objective outbreak pandemic predict Prevent public health quarantine ranking Region regions required Result root secure social distancing Space spatiotemporal spread of COVID-19 strain Travel vaccination variant Virology [DOI] 10.1136/bmjopen-2020-048279 PMC 바로가기 [Article Type] Epidemiology